Gadopentetate Dimeglumine

Synonyms: Gadopentetic acid dimeglumine, Gd-DTPA, Meglumine gadopentetate

Gadopentetate Dimeglumine (Gadopentetic acid dimeglumine, Gd-DTPA, Meglumine gadopentetate), a complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid, is an extracellular intravenous contrast agent used in magnetic resonance imaging.

Gadopentetate Dimeglumine Chemical Structure

Gadopentetate Dimeglumine Chemical Structure

CAS: 86050-77-3

Selleck's Gadopentetate Dimeglumine has been cited by 1 publication

Purity & Quality Control

Batch: S485201 DMSO] 100 mg/mL] false] Water] 10 mg/mL] false] ] ] false Purity: 99.98%
99.98

Gadopentetate Dimeglumine Related Products

Biological Activity

Description Gadopentetate Dimeglumine (Gadopentetic acid dimeglumine, Gd-DTPA, Meglumine gadopentetate), a complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid, is an extracellular intravenous contrast agent used in magnetic resonance imaging.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02775786 Active not recruiting
Pancreatic Adenocarcinoma
Columbia University
November 2013 Not Applicable
NCT00999258 Unknown status
Glomerular Filtration Rate|Chronic Allograft Nephropathy
Temple University|Wyeth is now a wholly owned subsidiary of Pfizer
September 2009 Phase 4
NCT00880061 Terminated
Brain Neoplasm|Glioma
National Institute of Neurological Disorders and Stroke (NINDS)|National Institutes of Health Clinical Center (CC)
April 7 2009 Phase 1

Chemical Information & Solubility

Molecular Weight 938 Formula

C14H18GdN3O10.2C7H17NO5.2H

CAS No. 86050-77-3 SDF --
Smiles CNCC(O)C(O)C(O)C(O)CO.CNCC(O)C(O)C(O)C(O)CO.OC(=O)CN1CCN2CCN(CC(O)=O)CC(=O)O[Gd](OC(=O)C2)OC(=O)C1
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 100 mg/mL ( (106.6 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 10 mg/mL


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In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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