Fenoldopam mesylate

Synonyms: SKF 82526 (mesylate), Fenoldopam methanesulfonate, Corlopam mesylate

Fenoldopam (SKF 82526, Corlopam) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.

Fenoldopam mesylate Chemical Structure

Fenoldopam mesylate Chemical Structure

CAS: 67227-57-0

Selleck's Fenoldopam mesylate has been cited by 1 publication

Purity & Quality Control

Batch: Purity: 99.96%
99.96

Fenoldopam mesylate Related Products

Choose Selective Dopamine Receptor Inhibitors

Biological Activity

Description Fenoldopam (SKF 82526, Corlopam) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
Targets
D1 receptor [1]
In Vivo
In vivo Fenoldopam (20 μg/kg) induced a marked decrease in systolic blood pressure, diastolic blood pressure and heart rate[1].
Animal Research Animal Models Conscious sinoaortic denervated dogs
Dosages 0.9% NaCl
Administration i.v.

Chemical Information & Solubility

Molecular Weight 401.86 Formula

C16H16ClNO3.CH4O3S

CAS No. 67227-57-0 SDF Download Fenoldopam mesylate SDF
Smiles CS(=O)(=O)O.C1CNCC(C2=CC(=C(C(=C21)Cl)O)O)C3=CC=C(C=C3)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 80 mg/mL ( (199.07 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


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In vivo
Batch:

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In vivo Formulation Calculator

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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