Fenbufen

Catalog No.S4526 Synonyms: Lederfen, CL-82204

Fenbufen Chemical Structure

Molecular Weight(MW): 254.28

Fenbufen is an orally active phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug.

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Biological Activity

Description Fenbufen is an orally active phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug.
Targets
cyclo-oxygenase [3] ATP systhesis [1]
0.88 μM(Ki)
In vivo Fenbufen and its metabolites could be involved in mitochondrial toxicity through inhibition of ATP synthesis[1]. Fenbufen inhibited prostaglandin release by 80% and reduced rates of protein synthesis in normal muscle and in muscle undergoing hypertrophy in response to tenotomy of a synergist[3].

Protocol

Solubility (25°C)

In vitro DMSO 50 mg/mL (196.63 mM)
Ethanol 50 mg/mL (196.63 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 254.28
Formula

C16H14O3

CAS No. 36330-85-5
Storage powder
Synonyms Lederfen, CL-82204

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