Home Microbiology Anti-infection chemical Sulfadoxine For research use only.

Sulfadoxine

Synonyms: Sulphadoxine

Sulfadoxine (Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.

Sulfadoxine Chemical Structure

Sulfadoxine Chemical Structure

CAS: 2447-57-6

Purity & Quality Control

Batch: S251101 DMSO] 62 mg/mL] false] Water] Insoluble] false] Ethanol] Insoluble] false Purity: 99.5%
99.5

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Biological Activity

Description Sulfadoxine (Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.
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NCT06162078 Recruiting
Maternal Malaria During Pregnancy - Baby Not Yet Delivered
Groupe de Recherche Action en Sante
 August 25 2023 --
NCT05979896 Recruiting
Malaria
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 July 28 2023 Phase 4
NCT05478954 Active not recruiting
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Malaria
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NCT04577469 Unknown status
Bioequivalence
Emzor Pharmaceutical Industries Limited
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Chemical Information & Solubility

Molecular Weight 310.33378 Formula

C12H14N4O4S
CAS No. 2447-57-6 SDF Download Sulfadoxine SDF
Smiles COC1=C(N=CN=C1OC)NS(=O)(=O)C2=CC=C(C=C2)N
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 62 mg/mL ( (199.78 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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