PCNA Antibody Chemical Structure
Molecular Weight: 29 kDa

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Customer Reviews(1)

Product Information

Product Description

Biological Activity

PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. It is found in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Chemical Information

Molecular Weight (MW) 29 kDa
Formula

This polyclonal antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to residues

CAS No.
Synonyms PCNA antibody; MGC8367 antibody; Proliferating cell nuclear antigen antibody; Cyclin antibody
Storage 2 years -20°CPowder
2 weeks4°Cin DMSO
6 months-80°Cin DMSO
Chemical Name

Research Area

Customer Reviews (1)


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Source PCNA Antibody purchased from Selleck
Method
Cell Lines
Concentrations
Incubation Time
Results

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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