Leucovorin Calcium Chemical Structure
Molecular Weight: 601.58

Related Compound Libraries

Leucovorin Calcium is available in the following compound libraries:

Product Information

Product Description

Biological Activity

Human lymphoid cell lines were studied for leucovorin requirements to protect from methotrexate (MTX)-induced growth suppression. Over a 72h continuous exposure leucovorin provided better protection to the cell lines LAZ-007 and RAJI than to the cell lines CCRF-CEM and MOLT-4. [1]
Leucovorin is a compound similar to folic acid, which is a necessary vitamin.  It has been around and in use for many decades. Leucovorin is a medication frequently used in combination with the chemotherapy drugs fluoruracil and methotrexate.  Leucovorin is a chemoprotectant, not a chemotherapy drug, however,  it is used in addition to these chemotherapy drugs to enhance anti cancer effects (with fluorouracil) or to help prevent or lessen side effects (with methotrexate). [2]

Chemical Information

Download Leucovorin Calcium SDF
Molecular Weight (MW) 601.58
Formula

C21H25CaN7O7.5H2O

CAS No. 6035-45-6
Synonyms Calcium, Calcium Folinatc, Citrovorum Factor
Storage 2 years -20°CPowder
2 weeks4°Cin DMSO
6 months-80°Cin DMSO
Chemical Name

Research Area

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