Floxuridine

Catalog No.S1299 Synonyms: Deoxyfluorouridine, FUDR, NSC 27640

Floxuridine Chemical Structure

Molecular Weight(MW): 246.19

Floxuridine is an antineoplastic antimetabolite, used in the treatment of colon carcinoma and colorectal cancer that has metastasized to the liver.

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Biological Activity

Description Floxuridine is an antineoplastic antimetabolite, used in the treatment of colon carcinoma and colorectal cancer that has metastasized to the liver.
In vitro

Floxuridine exhibits higher affinity for PEPT1 than the corresponding 5'-O-mono amino acid ester prodrugs. [1] Floxuridine combined with Leucovorin results in synergistic inhibitory effects on growth of human T-lymphoblast leukemia cells. [2] Floxuridine significantly inhibits the uptake of both [(3)H]-inosine and [(3)H]-adenosine (60-70% of control), while its amino acid ester prodrugs including Val, Phe, Pro, Asp, and Lys esters exhibits markedly decreased inhibition potency (10-30% of control). [3] Floxuridine inhibits cell proliferation by more than 50% relative to the untreated control cells at 36 days, the cell numbers still increases fourfold compared with the initial cell density. Floxuridine results in prolonged effects on the proliferation of human Tenon's capsule fibroblasts in vitro. [4] Floxuridine (FUDR) is an ideal drug for hepatic arterial infusion (HAI) due to its short half life, steep dose response curve, high total body clearance, and high hepatic extraction. [5]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
CCRF-CEM cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV;1Z2hvXGW|dHXkJIlvKH[rdILvJIZweiC2aHWgbY5pcWKrdHnvckBw\iClZXzsJIdzd3e2aDDv[kBpfW2jbjDUJIx6dXCqb3LsZZN1d2mmIFPDVmYuS0WPIHPlcIwhdGmwZTCoRXRESyCFQ1ygNVE6MSxiSVO1NF0xNjVizszN NV;KeHNHOTF7MEm3NVY>
CCRF-CEM MknQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXXJckB3cXS{bzDjc45k\W62cnH0bY9vKHKncYXpdoVlKG[xcjC1NEUhcW6qaXLpeIlwdiCxZjDndo94fGhib3[gbJVu[W5ibHX1b4VucWFiY3XscEBtcW6nIFPDVmYuS0WPIIfpeIghcFCDUDCoNE4zKHWwaYSvcWwqNCCJSUWwQVAvODByNjFOwG0> MoLmNVE2QTd2MES=
LNCaP cells MUDDfZRwfG:6aXPpeJkh[XO|YYm= M16yOWN6fG:2b4jpZ{Bkd26lZX70doF1cW:wIHnuJJBzd3O2YYTlJJNx\WOrZnnjJIFvfGmpZX6gLHBUSSlicILv[JVkcW6pIHj1cYFvKEyQQ3HQJINmdGy|LDDJR|UxRTBwME[5NkDPxE1? Mn3GNVIyPjFzNUe=
TSU cells M1PVfGN6fG:2b4jpZ4l1gSCjc4PhfS=> NVSwOVlHS3m2b4TvfIlkKGOxbnPlcpRz[XSrb36gbY4hdm:wIIDyc5N1[XSnIIPw[YNq\mmlIHHueIlo\W5iKGDTRUkheHKxZIXjbY5oKGi3bXHuJHRUXSClZXzsd{whUUN3ME2wMlA2QCEQvF2= NWPHV3FvOTJzNkGxOVc>
KBALB cell NHr5OGlEgXSxdH;4bYNqfHliYYPzZZk> M2TDUGlvKH[rdILvJINmdGxiY4n0c5RwgGmlaYT5JIFo[Wmwc4SgT2JCVEJiY3XscEBtcW6nIDj0doFve2[xcn3l[EBncWK{b3LsZZN1KHOjcnPvcYEh[2WubDDsbY5mMSxiQ1O1NF03NjByRT2wOUDPxE1? MmT3NVI3OjByN{[=
KBALB-STK cell MmLUR5l1d3SxeHnjbZR6KGG|c3H5 NXO3e4lkUW5idnn0do8h[2WubDDjfZRwfG:6aXPpeJkh[WejaX7zeEBMSkGOQj3TWGsh[2WubDDsbY5meyCneIDy[ZN{\WRiaX6gTHNXNTFiVFusJGlEPTB;OD64NGUuODVizszN MnHXNVI3OjByN{[=
L1210 mouse leukemia cells MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVX2dlR4OjRiaB?= NFH4bIdIem:5dHigbY5pcWKrdHnvckBqdiCOMUKxNEBud3W|ZTDs[ZVs\W2rYTDj[YxteyCjZoTldkAzPCCqIITy[YF1dWWwdDygTWM2OD1yLkCwOFEh|ryP NYTDbIRVOTF5MkixPVM>
L1210 mouse leukemia cells MlzwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWe0PEBp MYrHdo94fGhiaX7obYJqfGmxbjDpckBNOTJzMDDtc5V{\SCuZYXr[Y1q[SClZXzsd{Bi\nSncjC0PEBpeiC2cnXheI1mdnRuIFnDOVA:OC5yMEC2OEDPxE1? NUL0cW95OTF5MkixPVM>
L5178Y cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWXDc41x[XKjdHn2[UBqdmirYnn0bY9vKG:oIFy1NVc5YSClZXzsJIdzd3e2aDDpckB3cXS{bzCoZ49v[2WwdILheIlwdiC{ZYH1bZJm\CCob4KgOVAmKGmwaHnibZRqd25rLDDJR|UxRTBwMECwO|Yh|ryP NHz4S5c3Pzd7MEC3
L5178Y cells NIjlPGxHfW6ldHnvckBie3OjeR?= M1[zVWlvcGmkaYTvdpkh[2:wY3XueJJifGmxbjDv[kBkd22yb4Xu[EB4[XNiY3HsZ5Vt[XSnZDDvckBNPTF5OGmgZ4VtdHNiYomgX|E1S12OZYWgbY5kd3Kyb4LheIlwdixiSVO1NF0zKM7:TR?= NEHmbYo5OjR4MkK5
L1210 mouse leukemia cells MWPGeY5kfGmxbjDhd5NigQ>? NFvlOFIzKGh? M{O2PXRpgW2rZInsZZRmKHO7boToZZNmKGmwaHnibZRqd25iaX6gUFEzOTBibX;1d4UhdGW3a3XtbYEh[2WubIOgZYZ1\XJiMjDodkB1emWjdH3lcpQtKEmFNUC9NE4xODd7IN88US=> M3KzblEyPzJ6MUmz
LM cells NGDOdWpHfW6ldHnvckBie3OjeR?= M3X3elIhcA>? MoLkWIh6dWmmeXzheIUhe3mwdHjhd4UhcW6qaXLpeIlwdiCrbjD0bJlucWSrbnWgb4lv[XOnIHTl[olkcWWwdDDMUUBk\WyuczDh[pRmeiB{IHjyJJRz\WG2bXXueEwhUUN3ME21MlQh|ryP NWTMSGpTOTF5MkixPVM>
HT1080 cells MWrGeY5kfGmxbjDhd5NigQ>? M3[1dWN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIWFExQDBiY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxRTBwMUig{txO NV\ORm5IOTd6MESyN|E>
L1210 cells NYW0d3g5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGGwXJI4OiCq MVHDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViTEGyNVAh[2WubIOgRXRESyCFQ1yyNVkh[XO|ZYPz[YQh[XNiZ4Lve5RpKHKnZIXjeIlwdiCjZoTldkA4OiCqcoOsJGlEPTB;MD6wNVIh|ryP MUixO|k6PzNzOR?=
HL60 cells NGjxWldIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUi3NkBp M3LLfWN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIUFYxKGOnbHzzJGFVS0NiQ1PMJFI1OCCjc4Pld5Nm\CCjczDndo94fGhicnXkeYN1cW:wIHHmeIVzKDd{IHjyd{whUUN3ME2wMlAyOiEQvF2= M13iZlE4QTl5M{G5
CCRF-CEM cells MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NU\pOXNuPzJiaB?= NH;ydJlEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gR2NTTi2FRV2gZ4VtdHNiQWTDR{BES0xiMUG5JIF{e2W|c3XkJIF{KGe{b4f0bEBz\WS3Y4Tpc44h[W[2ZYKgO|IhcHK|LDDJR|UxRTBwMEG3JO69VQ>? MXGxO|k6PzNzOR?=
L1210 cells NXj0OVVQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlrtO|IhcA>? NX7pUlFpS3m2b4P0ZZRq[yCjY4Tpeol1gSCrbjDtc5V{\SCOMUKxNEBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oIHPlcIwh\3Kxd4ToJIFnfGW{IEeyJIhzeyxiSVO1NF0xNjBzMjFOwG0> NVHIcZJNOThyN{i3OVc>
HL60 cells MkjvS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWO3NkBp MojXR5l1d3O2YYTpZ{Bi[3Srdnn0fUBqdiCqdX3hckBJVDZyIHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4Yh[2WubDDndo94fGhiYX\0[ZIhPzJiaILzMEBKSzVyPUCuNFEzKM7:TR?= NYXjWoNROThyN{i3OVc>
CCRF-CEM cells MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NF3KZ4M4OiCq MYnDfZRwe3SjdHnjJIFkfGm4aYT5JIlvKGi3bXHuJGNEWkZvQ1XNJINmdGy|IHHzd4V{e2WmIHHzJIlvcGmkaYTpc44hd2ZiY3XscEBoem:5dHigZYZ1\XJiN{KgbJJ{NCCLQ{WwQVAvODF5IN88US=> MnPRNVgxPzh5NUe=
CCRF-CEM cells MoD2SpVv[3Srb36gZZN{[Xl? NIfZU2M1QCCq MnToRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFPDVmYuS0WPIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMEC2N|Eh|ryP NETvSIEyQTd2NEi1PC=>
K562 cells NUDXXlJXTnWwY4Tpc44h[XO|YYm= M2DKTFQ5KGh? NXnLV|lsSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGs2PjJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC55OUSzN{DPxE1? M4jIUVE6PzR2OEW4
MOLT4 cells NIj3UHdHfW6ldHnvckBie3OjeR?= M1vuTFQ5KGh? MV\BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTV;MWFQh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4xOzl6MTFOwG0> M3nGU|E6PzR2OEW4
RPMI8266 cells MU\GeY5kfGmxbjDhd5NigQ>? MX:0PEBp M1K3V2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDSVG1KQDJ4NjDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1yLke5OFM{KM7:TR?= NVXRRXFqOTl5NES4OVg>
human SR cells M2LKTGZ2dmO2aX;uJIF{e2G7 MofLOFghcA>? Mm[yRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPSJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUCuNFEzPTlizszN M1:4Z|E6PzR2OEW4
A549 cells MmLkSpVv[3Srb36gZZN{[Xl? NW\QdYNQPDhiaB?= MYPBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQUW0PUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2wMlAyOjV7IN88US=> M1jnSFE6PzR2OEW4
EKVX cells NYjF[HlJTnWwY4Tpc44h[XO|YYm= MUG0PEBp Ml;ORY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFXLWngh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NVAh|ryP M{DXRVE6PzR2OEW4
HOP62 cells MmH1SpVv[3Srb36gZZN{[Xl? NFm0Nm81QCCq NHPGc4ZCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTG9RPjJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5yMkWxNkDPxE1? MlWwNVk4PDR6NUi=
HOP92 cells Mn7rSpVv[3Srb36gZZN{[Xl? NXP6NYxCPDhiaB?= MmHpRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjPVFkzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvPzl2M{Og{txO MV[xPVc1PDh3OB?=
NCI-H226 cells NV36[YZHTnWwY4Tpc44h[XO|YYm= M2fpdlQ5KGh? MnezRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF7DTU1JOjJ4IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7 M4rLXVE6PzR2OEW4
NCI-H23 NH3OXpNHfW6ldHnvckBie3OjeR?= MkLWOFghcA>? M1TSV2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDOR2kuUDJ|IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTFyIN88US=> MX2xPVc1PDh3OB?=
NCI-H322 NX7icGpVTnWwY4Tpc44h[XO|YYm= MV:0PEBp NUTGfnJ7SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KM{KyUUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2wMlUxOTF7IN88US=> NH\HUI0yQTd2NEi1PC=>
NCI-H460 NHLyfG5HfW6ldHnvckBie3OjeR?= Ml;XOFghcA>? MoSxRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF7DTU1JPDZyIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwNUCxNVkh|ryP NEewNHgyQTd2NEi1PC=>
NCI-H522 MmrZSpVv[3Srb36gZZN{[Xl? NG\sdGg1QCCq M4PvOmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDOR2kuUDV{MjDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1yLkCwNkDPxE1? MlywNVk4PDR6NUi=
COLO205 cells MlW3SpVv[3Srb36gZZN{[Xl? M2jEeFQ5KGh? Mne1RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFPPUG8zODViY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:Oi53MUG4PUDPxE1? NUDhPZNFOTl5NES4OVg>
HCC2998 cells NF7oWYNHfW6ldHnvckBie3OjeR?= MVq0PEBp MknSRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDR|I6QThiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OS53OES4PUDPxE1? MVexPVc1PDh3OB?=
HCT116 cells MmjnSpVv[3Srb36gZZN{[Xl? MVm0PEBp MnT6RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFEyPiClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjByMTFOwG0> MlzGNVk4PDR6NUi=
HCT15 cells NETlNIVHfW6ldHnvckBie3OjeR?= NX7QNY1RPDhiaB?= MnHKRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFE2KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvOTJ3OEmg{txO M1fVRlE6PzR2OEW4
HT-29 cells M37QXWZ2dmO2aX;uJIF{e2G7 NI\CTGY1QCCq MX\BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSGStNlkh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NU46QTV{NjFOwG0> M1jUOlE6PzR2OEW4
KM12 cells NF[ycmtHfW6ldHnvckBie3OjeR?= NIK1UFg1QCCq NVi4VHllSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGtOOTJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:Oi53MUG4PUDPxE1? NVza[pllOTl5NES4OVg>
SW620 cells MVfGeY5kfGmxbjDhd5NigQ>? NETJR2Y1QCCq NX3FNZhOSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNYPjJyIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTZwM{C5OVch|ryP Mn\GNVk4PDR6NUi=
SF268 cells MYrGeY5kfGmxbjDhd5NigQ>? Moe2OFghcA>? NUW5fW57SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNHOjZ6IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTFyIN88US=> M2KwblE6PzR2OEW4
SF295 cells MXvGeY5kfGmxbjDhd5NigQ>? MXq0PEBp NXTUdIk4SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNHOjl3IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMEGyOVkh|ryP NW[0XYNkOTl5NES4OVg>
SF539 cells MV7GeY5kfGmxbjDhd5NigQ>? MVK0PEBp M2G0ZmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTSlU{QSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjB|OUixJO69VQ>? NX\je5l5OTl5NES4OVg>
SNB19 cells MljGSpVv[3Srb36gZZN{[Xl? Mm\XOFghcA>? NWHXc|dwSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNPSjF7IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTFwOUm1NlYh|ryP MkftNVk4PDR6NUi=
SNB75 cells M3y0dmZ2dmO2aX;uJIF{e2G7 MlnlOFghcA>? NHXYNo1CdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV25DPzViY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5zOUm1N{DPxE1? MUixPVc1PDh3OB?=
U251 cells NF;pVnNHfW6ldHnvckBie3OjeR?= NG\DRmw1QCCq MnewRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGWyOVEh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4yOjV6OTFOwG0> NW\WWph7OTl5NES4OVg>
LOXIMVI cells MWrGeY5kfGmxbjDhd5NigQ>? M1fy[FQ5KGh? NWPaXoxWSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGxQYEmPVlmgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MD6wNlUyOiEQvF2= MkfiNVk4PDR6NUi=
MALME-3M cells Ml\PSpVv[3Srb36gZZN{[Xl? MYG0PEBp NHHxb5dCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUWFNVUVvM12gZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;Nz65OFMzQCEQvF2= MmP6NVk4PDR6NUi=
M14 cells MWPGeY5kfGmxbjDhd5NigQ>? NEHWUZc1QCCq NF25UIJCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUVE1KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvOTV6NEmg{txO NXfUZ2R7OTl5NES4OVg>
SK-MEL-2 cells M{LnSGZ2dmO2aX;uJIF{e2G7 MXe0PEBp MkLXRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPLMW1GVC1{IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTFyIN88US=> MUSxPVc1PDh3OB?=
SK-MEL-28 cells MmDISpVv[3Srb36gZZN{[Xl? NWPUfnlmPDhiaB?= Mli1RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPLMW1GVC1{ODDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1zLkm5OVI3KM7:TR?= MWqxPVc1PDh3OB?=
SK-MEL-5 cells MVrGeY5kfGmxbjDhd5NigQ>? NVTwXFZ3PDhiaB?= NETvO5ZCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV2suVUWOLUWgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MD6xPVk2OyEQvF2= NX\ZOGlKOTl5NES4OVg>
UACC257 cells MWLGeY5kfGmxbjDhd5NigQ>? M2K1cFQ5KGh? NVrae|ZLSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHVCS0N{NUegZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;Mz6xOlIzQCEQvF2= MUGxPVc1PDh3OB?=
UACC62 cells MXnGeY5kfGmxbjDhd5NigQ>? M1TRUVQ5KGh? M3PvU2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDVRWNEPjJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5yM{m4NUDPxE1? M3HOSVE6PzR2OEW4
IGROV1 cells NWnGd2VwTnWwY4Tpc44h[XO|YYm= NHf6UJk1QCCq MYjBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSVfSU3YyKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVIvPTFzOEmg{txO NYTpNHl7OTl5NES4OVg>
OVCAR-3 cells NX\veFdpTnWwY4Tpc44h[XO|YYm= NVHiNmpHPDhiaB?= MY\BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iT2\DRXIuOyClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0zNjVzMUi5JO69VQ>? MlvtNVk4PDR6NUi=
OVCAR4 cells NYrqNIpNTnWwY4Tpc44h[XO|YYm= M{HxUlQ5KGh? NFLUd3VCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gU3ZESVJ2IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTFyIN88US=> NH2wbHIyQTd2NEi1PC=>
OVCAR5 cells NV:1bpFxTnWwY4Tpc44h[XO|YYm= MmTmOFghcA>? NWPhPXY1SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG9XS0GUNTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD14LkOwPVU4KM7ebR?= MWSxPVc1PDh3OB?=
OVCAR8 cells MofCSpVv[3Srb36gZZN{[Xl? NEjNNFQ1QCCq NWPzXJNXSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG9XS0GUODDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1yLkGyOVg6KM7:TR?= NGnlUnUyQTd2NEi1PC=>
SKOV3 cells NH;GN4VHfW6ldHnvckBie3OjeR?= NE\yOVI1QCCq NWXQdGFHSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNMV1Z|IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTFwOUm1NlYh|ryP M{Dwb|E6PzR2OEW4
786-0 cells NV;VW3JKTnWwY4Tpc44h[XO|YYm= M1Xt[VQ5KGh? NYjxdIZSSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJFc5Pi1yIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMTFOwG0> MVGxPVc1PDh3OB?=
A498 cells NES5S|VHfW6ldHnvckBie3OjeR?= MUK0PEBp MVfBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQUS5PEBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2xMlI2QDl|IN88US=> MmDDNVk4PDR6NUi=
ACHN cells NF22OnhHfW6ldHnvckBie3OjeR?= NFXRbXI1QCCq NFjOXIVCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gRWNJViClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjB|MU[yJO69VQ>? NUnVVpI4OTl5NES4OVg>
Caki1 cells MXzGeY5kfGmxbjDhd5NigQ>? MnrjOFghcA>? MUPBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ3HrbVEh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4xOzF4MjFOwG0> M17q[FE6PzR2OEW4
SN12C cells NY\YR5d4TnWwY4Tpc44h[XO|YYm= NYfzenpjPDhiaB?= MlzZRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPONVJEKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvOTl7NUOg{txO MYixPVc1PDh3OB?=
TK10 cells M3PEN2Z2dmO2aX;uJIF{e2G7 NYf0enQ5PDhiaB?= NIjmNFhCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gWGsyOCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF02NjBzMUi3JO69VQ>? NY[3fldVOTl5NES4OVg>
UO31 cells NXPRWIk5TnWwY4Tpc44h[XO|YYm= M{nKZlQ5KGh? NYTYNIpGSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHVQOzFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5zMkW4PUDPxE1? M1q0WFE6PzR2OEW4
PC3 cells NVPMeGk4TnWwY4Tpc44h[XO|YYm= MX20PEBp NIPKU2pCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvOzF4MkOg{txO NF7EWZQyQTd2NEi1PC=>
DU145 cells NFLIWVhHfW6ldHnvckBie3OjeR?= NFfRZZA1QCCq M3n5fWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDEWVE1PSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjJ3MUG5JO69VQ>? MVmxPVc1PDh3OB?=
MCF7 cells MVnGeY5kfGmxbjDhd5NigQ>? NYjXTJpFPDhiaB?= NXu2cVI6SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5yME[zNUDPxE1? MmnkNVk4PDR6NUi=
NCI/ADR-RES cells MYDGeY5kfGmxbjDhd5NigQ>? MkDpOFghcA>? MULBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJM2FFWi2URWOgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MT6yOVg6OyEQvF2= NX\UVI9mOTl5NES4OVg>
MDA-MB-231 cells M4fCSWZ2dmO2aX;uJIF{e2G7 NIX2UYs1QCCq M{nFTWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvMkOxJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUOuPVgyODdizszN NXHBXHc6OTl5NES4OVg>
Hs 578T cells MVPGeY5kfGmxbjDhd5NigQ>? M{\p[lQ5KGh? M4TCOmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDId{A2PziWIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTNwOUixNFch|ryP NYHMNGlJOTl5NES4OVg>
MDA-MB-435 cells NXvWR3BtTnWwY4Tpc44h[XO|YYm= M37wbVQ5KGh? NYP4cYJLSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj20N|Uh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9N{4yPjJ{ODFOwG0> NWfGc21ROTl5NES4OVg>
MDA-N cells MYPGeY5kfGmxbjDhd5NigQ>? MUO0PEBp NGHTRW5CdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUWRCNU5iY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OS5{NUi5N{DPxE1? NWH3bWluOTl5NES4OVg>
BT549 cells NGHlemNHfW6ldHnvckBie3OjeR?= NUjqNWlXPDhiaB?= M3;NW2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDCWFU1QSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0yKM7:TR?= MkPBNVk4PDR6NUi=
T47D cells NInac5FHfW6ldHnvckBie3OjeR?= NGDRU3c1QCCq NHvXbmxCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gWFQ4TCClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0yNjJ3OEmzJO69VQ>? MmPoNVk4PDR6NUi=
HepG2 cells MlnMR5l1d3SxeHnjbZR6KGG|c3H5 M1\SXlczKGh? NHfJd2ZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCHQ{WwQVE5Njh2IN88US=> MkT2NVk6OTd3Mki=
A549 cells M4L2O2N6fG:2b4jpZ4l1gSCjc4PhfS=> NEnaWHU4OiCq MYLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGVEPTB;OT63OEDPxE1? NIHaTnEyQTlzN{WyPC=>
LAC cells MV3DfZRwfG:6aXPpeJkh[XO|YYm= MWi3NkBp Mn;QR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUGFEKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGVEPTB;M{KuNFkh|ryP NVzPPVROOTl7MUe1Nlg>
HeLa cells NIHPe|BEgXSxdH;4bYNqfHliYYPzZZk> MWC3NkBp M4DkcWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhTUN3ME2xNE4zPiEQvF2= MYexPVkyPzV{OB?=
MDA-MB-231 cells M3nBS2N6fG:2b4jpZ4l1gSCjc4PhfS=> MYjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvMkOxJINmdGy|IH;2[ZJmgHC{ZYPzbY5oKHW{b3vpcoF{\SCybHHzcYlvd2enbjDhZ5RqfmG2b4KsJGlEPTB;MD6yNUDPxE1? MUWyNFM3OzF|MB?=
human ACHN cells MWjGeY5kfGmxbjDhd5NigQ>? MVrBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQVPIUkBk\WyuczDifUBUWkJiYYPzZZktKEeLNUC9Nk4yKM7:TR?= M1jJbVIxPzN{OEGw
PC3 cells NUfJb5dwTnWwY4Tpc44h[XO|YYm= NV;mV4F6SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHBEOyClZXzsd{BjgSCVUlKgZZN{[XluIFfJOVA:PC57NzFOwG0> MnG5NlA4OzJ6MUC=
MDA-MB-231 cells Mm\CSpVv[3Srb36gZZN{[Xl? NF6yfFVCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDifUBUWkJiYYPzZZktKEeLNUC9NE4yPiEQvF2= M1XweVIxPzN{OEGw
FM3A cells NEDOXplHfW6ldHnvckBie3OjeR?= M2XLRVIh\GG7cx?= MWrDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViRl2zRUBk\WyuczDh[pRmeiB{IHThfZMh[nliY3;1cJRmeiClb4XueIlv\yCjbnHsfZNqeyxiSVO1NF0xNjByOUSg{txO M2T1eFIyOzNyMEG0
HeLa cells MV\GeY5kfGmxbjDhd5NigQ>? NWXqcFFTS3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMhcW5icILld4Vv[2Vib3[gNlAhfU1idHj5cYllcW6nLDDJR|UxRThwNTFOwG0> NUnmOI5DOjF|M{CwNVQ>
LLC cells NGTib2hEgXSxdH;4bYNqfHliYYPzZZk> Mm\CNlQhcA>? NYTpbo06S3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhVEyFIHPlcIx{KGGodHXyJFI1KGi{czDifUBz\XOjeoXybY4h[XO|YYmsJGlEPTB;MUSuNkDPxE1? NWLG[XlGOjF3M{[0OFg>
LLC cells NUnJclZNS3m2b4TvfIlkcXS7IHHzd4F6 MmnxO|IhcA>? NFKyUIREgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBNVENiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JJJme2G8dYLpckBie3OjeTygTWM2OD1{IN88US=> Mnf4NlE2OzZ2NEi=
RAW264.7 cells NIfaOFhEgXSxdH;4bYNqfHliYYPzZZk> NVnTVm1JPzJiaB?= NFrVWmNEgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBTSVd{NkSuO{Bk\WyuczDh[pRmeiB5MjDodpMh[nlicnXzZZp2emmwIHHzd4F6NCCLQ{WwQVMxKM7:TR?= M13Pb|IyPTN4NES4
A549 cells NYf1VGZ7S3m2b4TvfIlkcXS7IHHzd4F6 Ml7HO|IhcA>? M4f3XWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB3cWGkaXzpeJkh[W[2ZYKgO|IhcHK|IHL5JHdUXC16IHHzd4F6NCCLQ{WwQVAvODR5IN88US=> NGm2TpIzOjJ2OEi1Oi=>
A2780 cells MXjDfZRwfG:6aXPpeJkh[XO|YYm= MXm1JIRigXN? NVLOTJJ5S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTJ5OECgZ4VtdHNiYX\0[ZIhPSCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NF0xNjB{NjFOwG0> NVP3T2pzOjJ5M{i2N|Y>
LMTK cells MlPNR5l1d3SxeHnjbZR6KGG|c3H5 NWriUJU{PSCmYYnz M{ToeWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KHSqeX3p[Ilv\SCtaX7hd4Uu\GWoaXPp[Y51KG2xdYPlJGxOXEtiY3XscJMh[W[2ZYKgOUBl[Xm|IHL5JG1VXCCjc4PhfUwhUUN3ME20MlUh|ryP MkXXNlI4Ozh4M{[=
A549 cells MkfWR5l1d3SxeHnjbZR6KGG|c3H5 MYe3NkBp NHL0TIlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFczKGi{czDifUBucWO{b4DsZZRmKHKnYXTldkBu\XSqb3SsJGlEPTB;MD6wNVI1KM7:TR?= MV6yNlg1PzBzOR?=
CEM cells M3rySWZ2dmO2aX;uJIF{e2G7 M{LJWlczKGh? NH3KbI9EgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gR2VOKGOnbHzzJIV5eHKnc4PpcochcHWvYX6gSW5VOSC2cnHud5BwenSncjDh[pRmeiB5MjDodpMh[nliY3XscEBkd3WwdHnu[{BqdiCycnXz[Y5k\SCxZjDORm1RWixiSVO1NF0xNjhizszN NHL5T24zOTh7MkiyPS=>
Hela cells M4\xV2Z2dmO2aX;uJIF{e2G7 MYq3NkBp MofRR5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjlUIEh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IHPlcIwh[2:3boTpcoctKEmFNUC9NE4xPSEQvF2= MYeyNVg6Ojh{OR?=
CEM/0 cells MWTGeY5kfGmxbjDhd5NigQ>? NYXDT|BYPzJiaB?= M12z[mN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDSW0wOCClZXzsd{Bi\nSncjC3NkBpenNiYomgZ4VtdCClb4XueIlv\yxiSVO1NF0xNjB{MjFOwG0> M4H2ZlIyQDl{OEK5
L1210/0 cells Ml;4SpVv[3Srb36gZZN{[Xl? NG\DdFY1QCCq NGjVd3hEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhdW:3c3WgUFEzOTBxMDDj[YxteyCjZoTldkA1QCCqcoOgZpkh[2WubDDjc5VvfGmwZzygTWM2OD1yLkCwNFkh|ryP MXmyNVg6Ojh{OR?=
MCF7 cells NV60WpY{S3m2b4TvfIlkcXS7IHHzd4F6 MXm3NkBp MUjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDTVmIh[XO|YYmsJGlEPTB;MUKuNVkh|ryP MlzGNlM5Pjd4MEO=
HeLa cells MX7DfZRwfG:6aXPpeJkh[XO|YYm= M171cVczKGh? NHvDeo1EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUC9Ok42KM7:TR?= NE\2XlQzOzh4N{[wNy=>
HL60 cells MX\Qdo9tcW[ncnH0bY9vKGG|c3H5 M1zO[FczKGh? MkDPRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKTE[wJINmdGy|IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTB;MD6yOEDPxE1? NUj5eot3OjV4NES2O|Q>
SW707 cells MoXCVJJwdGmoZYLheIlwdiCjc4PhfS=> M3G3V|czKGh? NYXuNnBVSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTW|cxPyClZXzsd{Bie3Onc4Pl[EBieyCpcn;3eIghcW6qaXLpeIlwdiCjZoTldkA4OiCqcoOgZpkhW1KEIH3leIhw\CxiSVO1NF0zOy56NjFOwG0> NHfhfY0zPTZ2NE[3OC=>
LoVo cells NFK5N4RRem:uaX\ldoF1cW:wIHHzd4F6 MVW3NkBp NVfDN5J2SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDMc3ZwKGOnbHzzJIF{e2W|c3XkJIF{KGe{b4f0bEBqdmirYnn0bY9vKGGodHXyJFczKGi{czDifUBUWkJibXX0bI9lNCCLQ{WwQVE6NjB5IN88US=> MlfWNlU3PDR4N{S=
BALB/3T3 cell M17hbnBzd2yrZnXyZZRqd25iYYPzZZk> NGPVN2U4OiCq MWXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IH3veZNmKEKDTFKvN3Q{KGOnbHzzJIF{e2W|c3XkJIF{KGe{b4f0bEBqdmirYnn0bY9vKGGodHXyJFczKGi{czDifUBUWkJibXX0bI9lNCCLQ{WwQVI{NjlizszN NUTyNI5JOjV4NES2O|Q>
HFF cells NYDTPHZjTnWwY4Tpc44h[XO|YYm= MojNO|IhcA>? MnLERY51cXCjcnHzbZRq[yCjY4Tpeol1gSCjZ3HpcpN1KFSxeH;wcIF{dWFiZ3;u[IlqKEGWQ1OgOVA5OzliaX7m[YN1\WRiaX6gTGZHKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDi[ZRiNWejbHHjeI9{cWSjc3WgdoVxd3K2ZYKg[4Vv\SCjc4PhfUwhTUN3ME2wMlkyKM7:TR?= NW\R[o1wOTd4OUi2NVg>
CCRFCEM cells MknqSpVv[3Srb36gZZN{[Xl? NF7XRphEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gR2NTTkOHTTDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTB;MD6yPUDPxE1? M4fS[|E4QDB2MkOx
RXF393 cells NIHpc5dHfW6ldHnvckBie3OjeR?= NF3ONHA1QCCq NEDxTHlCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gVnhHOzl|IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTNwOUixNFch|ryP MoLKNVk4PDR6NUi=
HL-60(TB) cells NEDq[WdHfW6ldHnvckBie3OjeR?= NWCz[XA5PDhiaB?= Mn3WRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjMMVYxMFSEKTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1yLkG5PVU{KM7:TR?= Mn7aNVk4PDR6NUi=
L1210 cells NGfTPJZHfW6ldHnvckBie3OjeR?= M4\sPFE2KG2rboO= MnLKTY5pcWKrdHnvckBw\iC2aIntbYR6dGG2ZTDzfY51cGG|ZTDpckBud3W|ZTDMNVIyOCClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJJRzcXSrdX2gdoVt\WG|ZTDmdo9uKFt3LUPIYYRmd3i7dYLp[Ilv\SCjZoTldkBxemWrbnP1ZoF1cW:wIH\vdkAyPSCvaX7zJIJ6KGyrcYXp[EB{[2mwdHnscIF1cW:wIHPveY51cW6pLDDJR|UxRTBwMECwOkDPxE1? MmPlNlE{OzByMUS=
Colo-357 cells M1PINWZ2dmO2aX;uJIF{e2G7 NYCzOJA2OTByIN88US=> NUfwO3hOOTVibXnudy=> MYjBZ5Rqfmm2eTDheEBOWlB3IHnuJIh2dWGwIFPvcI8uOzV5IHPlcIx{KGG|c3Xzd4VlKGG|IEWtSoRWVVBiYXPjeY12dGG2aX;uJIF1KDFyMDD1UUBi\nSncjCxOUBucW6| NXLVVHFbOjB7M{CxNlM>
KB cells MUHDfZRwfG:6aXPpeJkh[XO|YYm= MkHZO|IhcA>? NYH2d|R4S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hU0JiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JHNTSiCjc4PhfUwhUUN3ME24MlY6KM7:TR?= MmLnNlM5Pjd4MEO=

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 49 mg/mL (199.03 mM)
Water 49 mg/mL (199.03 mM)
Ethanol 10 mg/mL (40.61 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 246.19
Formula

C9H11FN2O5

CAS No. 50-91-9
Storage powder
in solvent
Synonyms Deoxyfluorouridine, FUDR, NSC 27640

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01749397 Active not recruiting Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7 National Cancer Institute (NCI) December 7 2012 Phase 1
NCT01525069 Recruiting Cholangiocarcinoma|Liver Neoplasms Washington University School of Medicine April 3 2012 Phase 1
NCT03500874 Recruiting Colorectal Cancer|Liver Metastases|HAI Sun Yat-sen University February 28 2018 Phase 3
NCT03069950 Recruiting Colorectal Adenocarcinoma Metastatic to the Liver Memorial Sloan Kettering Cancer Center|The Cleveland Clinic|Oregon Health and Science University|Queens Cancer Center of Queens Hospital|Washington University School of Medicine February 28 2017 Phase 2
NCT02529774 Not yet recruiting Resected Liver Metastases From Colorectal Cancer Ye Xu|Fudan University September 2015 Phase 2|Phase 3
NCT02402972 Recruiting Colorectal Cancer|Metastasis Xu jianmin|Zhejiang University|The Second Affiliated Hospital of Harbin Medical University|Ruijin Hospital|Fudan University February 2015 Phase 3

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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DNA/RNA Synthesis Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID