Floxuridine

Catalog No.S1299 Synonyms: Deoxyfluorouridine, FDUR, NSC 27640

Floxuridine Chemical Structure

Molecular Weight(MW): 246.19

Floxuridine is an antineoplastic antimetabolite, used in the treatment of colon carcinoma and colorectal cancer that has metastasized to the liver.

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Biological Activity

Description Floxuridine is an antineoplastic antimetabolite, used in the treatment of colon carcinoma and colorectal cancer that has metastasized to the liver.
In vitro

Floxuridine exhibits higher affinity for PEPT1 than the corresponding 5'-O-mono amino acid ester prodrugs. [1] Floxuridine combined with Leucovorin results in synergistic inhibitory effects on growth of human T-lymphoblast leukemia cells. [2] Floxuridine significantly inhibits the uptake of both [(3)H]-inosine and [(3)H]-adenosine (60-70% of control), while its amino acid ester prodrugs including Val, Phe, Pro, Asp, and Lys esters exhibits markedly decreased inhibition potency (10-30% of control). [3] Floxuridine inhibits cell proliferation by more than 50% relative to the untreated control cells at 36 days, the cell numbers still increases fourfold compared with the initial cell density. Floxuridine results in prolonged effects on the proliferation of human Tenon's capsule fibroblasts in vitro. [4] Floxuridine (FUDR) is an ideal drug for hepatic arterial infusion (HAI) due to its short half life, steep dose response curve, high total body clearance, and high hepatic extraction. [5]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
CCRF-CEM cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXHU[ZN1\WRiaX6geol1em9iZn;yJJRp\SCrbnjpZol1cW:wIH;mJINmdGxiZ4Lve5RpKG:oIHj1cYFvKFRibIntdIhw[myjc4TvbYQhS0OURj3DSW0h[2WubDDsbY5mKCiDVFPDJGNEVCBzMUmpMEBKSzVyPUCuOUDPxE1? NF7CVoIyOTlyOUexOi=>
CCRF-CEM NWLrNI9jT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlXjTY4hfmm2cn:gZ49v[2WwdILheIlwdiC{ZYH1bZJm\CCob4KgOVAmKGmwaHnibZRqd25ib3[g[5Jwf3SqIH;mJIh2dWGwIHzleYtmdWmjIHPlcIwhdGmwZTDDR3JHNUOHTTD3bZRpKGiSQWCgLFAvOiC3bnn0M41NMSxiR1m1NF0xNjByME[g{txO NEWzbo4yOTV7N{SwOC=>
LNCaP cells MWTDfZRwfG:6aXPpeJkh[XO|YYm= NVzwZ40xS3m2b4TvfIlkKGOxbnPlcpRz[XSrb36gbY4heHKxc4TheIUhe3CnY3nmbYMh[W62aXflckApWFODKTDwdo9lfWOrbnegbJVu[W5iTF7DZXAh[2WubIOsJGlEPTB;MD6wOlkzKM7:TR?= MWixNlE3OTF3Nx?=
TSU cells M4PyT2N6fG:2b4jpZ4l1gSCjc4PhfS=> NVHTe5NvS3m2b4TvfIlkKGOxbnPlcpRz[XSrb36gbY4hdm:wIIDyc5N1[XSnIIPw[YNq\mmlIHHueIlo\W5iKGDTRUkheHKxZIXjbY5oKGi3bXHuJHRUXSClZXzsd{whUUN3ME2wMlA2QCEQvF2= Ml;wNVIyPjFzNUe=
KBALB cell NVWwXJg6S3m2b4TvfIlkcXS7IHHzd4F6 MlPETY4hfmm2cn:gZ4VtdCCleYTveI95cWOrdImgZYdicW6|dDDLRmFNSiClZXzsJIxqdmViKITyZY5{\m:{bXXkJIZq[nKxYnzhd5Qhe2G{Y3;tZUBk\WyuIHzpcoUqNCCFQ{WwQVYvODCHLUC1JO69VQ>? MmX6NVI3OjByN{[=
KBALB-STK cell NIjlZpREgXSxdH;4bYNqfHliYYPzZZk> MlHoTY4hfmm2cn:gZ4VtdCCleYTveI95cWOrdImgZYdicW6|dDDLRmFNSi2VVFugZ4VtdCCuaX7ld{BmgHC{ZYPz[YQhcW5iSGPWMVEhXEtuIFnDOVA:QC56MFWtNFUh|ryP Mn;mNVI3OjByN{[=
L1210 mouse leukemia cells NX;RSIFnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFrkO2YzPCCq NGHpSGRIem:5dHigbY5pcWKrdHnvckBqdiCOMUKxNEBud3W|ZTDs[ZVs\W2rYTDj[YxteyCjZoTldkAzPCCqIITy[YF1dWWwdDygTWM2OD1yLkCwOFEh|ryP M2DiPFEyPzJ6MUmz
L1210 mouse leukemia cells M3\ER2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWO0PEBp MX;Hdo94fGhiaX7obYJqfGmxbjDpckBNOTJzMDDtc5V{\SCuZYXr[Y1q[SClZXzsd{Bi\nSncjC0PEBpeiC2cnXheI1mdnRuIFnDOVA:OC5yMEC2OEDPxE1? NWLFSmNKOTF5MkixPVM>
L5178Y cell MVrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYTQOYJXS2:vcHHyZZRqfmViaX7obYJqfGmxbjDv[kBNPTF5OGmgZ4VtdCCpcn;3eIghcW5idnn0do8hMGOxbnPlcpRz[XSrb36gdoVyfWm{ZXSg[o9zKDVyJTDpcohq[mm2aX;uLUwhUUN3ME2wMlAxODd4IN88US=> MYe2O|c6ODB5
L5178Y cells NXWzRo9uTnWwY4Tpc44h[XO|YYm= M{LGTmlvcGmkaYTvdpkh[2:wY3XueJJifGmxbjDv[kBkd22yb4Xu[EB4[XNiY3HsZ5Vt[XSnZDDvckBNPTF5OGmgZ4VtdHNiYomgX|E1S12OZYWgbY5kd3Kyb4LheIlwdixiSVO1NF0zKM7:TR?= Mon3PFI1PjJ{OR?=
L1210 mouse leukemia cells NIrNfJhHfW6ldHnvckBie3OjeR?= MlnoNkBp NELVSpVVcHmvaXT5cIF1\SC|eX70bIF{\SCrbnjpZol1cW:wIHnuJGwyOjFyIH3veZNmKGyndXvlcYliKGOnbHzzJIFnfGW{IEKgbJIhfHKnYYTt[Y51NCCLQ{WwQVAvODB5OTFOwG0> MV2xNVczQDF7Mx?=
LM cells NEjVVotHfW6ldHnvckBie3OjeR?= NIfqUIwzKGh? NF3NdVVVcHmvaXT5cIF1\SC|eX70bIF{\SCrbnjpZol1cW:wIHnuJJRpgW2rZHnu[UBscW6jc3Wg[IVncWOrZX70JGxOKGOnbHzzJIFnfGW{IEKgbJIhfHKnYYTt[Y51NCCLQ{WwQVUvPCEQvF2= NUf5NpVwOTF5MkixPVM>
HT1080 cells NGHwRpdHfW6ldHnvckBie3OjeR?= MnLyR5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjUNVA5OCClZXzsd{BjgSCPVGSgZZN{[XluIFnDOVA:OC5zODFOwG0> MnnYNVc5ODR{M{G=
L1210 cells MoLWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{Lz[lczKGh? M2nLZWN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBud3W|ZTDMNVIyOCClZXzsd{BCXEOFIFPDUFIyQSCjc4Pld5Nm\CCjczDndo94fGhicnXkeYN1cW:wIHHmeIVzKDd{IHjyd{whUUN3ME2wMlAyOiEQvF2= NXOzc4dKOTd7OUezNVk>
HL60 cells M2TCTWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NV23eGh6PzJiaB?= MmD1R5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjMOlAh[2WubIOgRXRESyCFQ1ygNlQxKGG|c3Xzd4VlKGG|IHfyc5d1cCC{ZXT1Z5Rqd25iYX\0[ZIhPzJiaILzMEBKSzVyPUCuNFEzKM7:TR?= MkTFNVc6QTd|MUm=
CCRF-CEM cells M4LN[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NV;QcVA4PzJiaB?= NIjBeZdEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gR2NTTi2FRV2gZ4VtdHNiQWTDR{BES0xiMUG5JIF{e2W|c3XkJIF{KGe{b4f0bEBz\WS3Y4Tpc44h[W[2ZYKgO|IhcHK|LDDJR|UxRTBwMEG3JO69VQ>? Mn;HNVc6QTd|MUm=
L1210 cells M1;hZ2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NF\sPXM4OiCq M1jMVmN6fG:|dHH0bYMh[WO2aY\peJkhcW5ibX;1d4UhVDF{MUCgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5pcWKrdHnvckBw\iClZXzsJIdzd3e2aDDh[pRmeiB5MjDodpMtKEmFNUC9NE4xOTJizszN M1\WclE5ODd6N{W3
HL60 cells NV3HXZM5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXy3NkBp NXT0SIpKS3m2b4P0ZZRq[yCjY4Tpeol1gSCrbjDoeY1idiCKTE[wJINmdGy|IHHzd4V{e2WmIHHzJIlvcGmkaYTpc44hd2ZiY3XscEBoem:5dHigZYZ1\XJiN{KgbJJ{NCCLQ{WwQVAvODF{IN88US=> MYGxPFA4QDd3Nx?=
CCRF-CEM cells MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWSxW3FSPzJiaB?= MVnDfZRwe3SjdHnjJIFkfGm4aYT5JIlvKGi3bXHuJGNEWkZvQ1XNJINmdGy|IHHzd4V{e2WmIHHzJIlvcGmkaYTpc44hd2ZiY3XscEBoem:5dHigZYZ1\XJiN{KgbJJ{NCCLQ{WwQVAvODF5IN88US=> NVLHNHlGOThyN{i3OVc>
CCRF-CEM cells NWLI[VBMTnWwY4Tpc44h[XO|YYm= MVm0PEBp MlXIRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFPDVmYuS0WPIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMEC2N|Eh|ryP NUTyUlFNOTl5NES4OVg>
K562 cells Mlu0SpVv[3Srb36gZZN{[Xl? MmfGOFghcA>? M3jDfmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDLOVYzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvPzl2M{Og{txO M1TKTlE6PzR2OEW4
MOLT4 cells M3W3TmZ2dmO2aX;uJIF{e2G7 NUjlXGZwPDhiaB?= MYrBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTV;MWFQh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4xOzl6MTFOwG0> M4DhS|E6PzR2OEW4
RPMI8266 cells NYXsUm9XTnWwY4Tpc44h[XO|YYm= M2i4Z|Q5KGh? NYfJTmNSSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHJRVUl6Mk[2JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUCuO|k1OzNizszN NFWxNWkyQTd2NEi1PC=>
human SR cells NVz5Z2hDTnWwY4Tpc44h[XO|YYm= NHnPUpQ1QCCq MWfBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU2KgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MD6wNVI2QSEQvF2= MmnmNVk4PDR6NUi=
A549 cells MnjpSpVv[3Srb36gZZN{[Xl? MUK0PEBp NV7NU|A2SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5yMUK1PUDPxE1? MkP3NVk4PDR6NUi=
EKVX cells NInoRWJHfW6ldHnvckBie3OjeR?= MkDsOFghcA>? Mnq5RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFXLWngh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NVAh|ryP NGrqflMyQTd2NEi1PC=>
HOP62 cells MXzGeY5kfGmxbjDhd5NigQ>? M3\GTlQ5KGh? MX;BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSF;QOlIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4xOjVzMjFOwG0> MXmxPVc1PDh3OB?=
HOP92 cells Mnm0SpVv[3Srb36gZZN{[Xl? NETERXc1QCCq MnT0RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjPVFkzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvPzl2M{Og{txO NGXvV28yQTd2NEi1PC=>
NCI-H226 cells NFrQe|dHfW6ldHnvckBie3OjeR?= NIXnfIY1QCCq NXPnOGp6SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG5EUS2KMkK2JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5 NF;CSlEyQTd2NEi1PC=>
NCI-H23 NWTzfGtUTnWwY4Tpc44h[XO|YYm= MY[0PEBp NF7jfXlCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUmNKNUh{MzDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1zMDFOwG0> M3qxNVE6PzR2OEW4
NCI-H322 M3[1dmZ2dmO2aX;uJIF{e2G7 MoC1OFghcA>? MmGzRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF7DTU1JOzJ{TTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1yLkWwNVE6KM7:TR?= NYD3cpB6OTl5NES4OVg>
NCI-H460 Ml7QSpVv[3Srb36gZZN{[Xl? NU[xVld6PDhiaB?= MXHBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJMWg1PjBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC53MEGxPUDPxE1? MYWxPVc1PDh3OB?=
NCI-H522 MX7GeY5kfGmxbjDhd5NigQ>? MV60PEBp Ml\TRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF7DTU1JPTJ{IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMECyJO69VQ>? M3nKXVE6PzR2OEW4
COLO205 cells M2W2d2Z2dmO2aX;uJIF{e2G7 MkWzOFghcA>? NWPwc4xLSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGNQVE9{MEWgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;Mj61NVE5QSEQvF2= NWDYVZM6OTl5NES4OVg>
HCC2998 cells NFP4OI9HfW6ldHnvckBie3OjeR?= MVK0PEBp MkfXRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDR|I6QThiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OS53OES4PUDPxE1? MljONVk4PDR6NUi=
HCT116 cells M2\yfGZ2dmO2aX;uJIF{e2G7 MkHMOFghcA>? NYfwb2F6SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhEXDFzNjDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1yLkCwNUDPxE1? NXPUeVNiOTl5NES4OVg>
HCT15 cells NFHzV5RHfW6ldHnvckBie3OjeR?= MmXqOFghcA>? MoW1RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFE2KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvOTJ3OEmg{txO M4TuOFE6PzR2OEW4
HT-29 cells MXPGeY5kfGmxbjDhd5NigQ>? NWDRUVFEPDhiaB?= MYHBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSGStNlkh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NU46QTV{NjFOwG0> NFTlXnMyQTd2NEi1PC=>
KM12 cells MYLGeY5kfGmxbjDhd5NigQ>? MnS1OFghcA>? M3iwd2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDLUVEzKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVIvPTFzOEmg{txO NF3BOpMyQTd2NEi1PC=>
SW620 cells MmW5SpVv[3Srb36gZZN{[Xl? M{HFW|Q5KGh? MlLsRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPXOlIxKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVYvOzB7NUeg{txO NHTIZmgyQTd2NEi1PC=>
SF268 cells MXTGeY5kfGmxbjDhd5NigQ>? MVK0PEBp NFjIRolCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV2YzPjhiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OTBizszN NVzFb20zOTl5NES4OVg>
SF295 cells NFLIZo1HfW6ldHnvckBie3OjeR?= NGHz[oU1QCCq M1nr[WFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTSlI6PSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjBzMkW5JO69VQ>? NEDzRWIyQTd2NEi1PC=>
SF539 cells MWHGeY5kfGmxbjDhd5NigQ>? MUe0PEBp M3XvNGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTSlU{QSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjB|OUixJO69VQ>? MnvmNVk4PDR6NUi=
SNB19 cells MYXGeY5kfGmxbjDhd5NigQ>? MlnkOFghcA>? Mn3ZRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPORlE6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVEvQTl3Mk[g{txO Mk\nNVk4PDR6NUi=
SNB75 cells NVnBbmFNTnWwY4Tpc44h[XO|YYm= M{n4bFQ5KGh? M3joZmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTUmI4PSClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0xNjF7OUWzJO69VQ>? MVmxPVc1PDh3OB?=
U251 cells MVrGeY5kfGmxbjDhd5NigQ>? MV[0PEBp NV6z[o54SW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHUzPTFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5zMkW4PUDPxE1? M1TTVlE6PzR2OEW4
LOXIMVI cells MUTGeY5kfGmxbjDhd5NigQ>? M2jjWFQ5KGh? M1vVU2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDMU3hKVV[LIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMEK1NVIh|ryP MVSxPVc1PDh3OB?=
MALME-3M cells NITy[3BHfW6ldHnvckBie3OjeR?= MVS0PEBp NX\IZ|NlSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG1CVE2HLUPNJINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUeuPVQ{OjhizszN MnW1NVk4PDR6NUi=
M14 cells NY\YZlRkTnWwY4Tpc44h[XO|YYm= M1jxNVQ5KGh? MkG4RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF2xOEBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2wMlE2QDR7IN88US=> NFnzO4QyQTd2NEi1PC=>
SK-MEL-2 cells NVjTSVd6TnWwY4Tpc44h[XO|YYm= MkTtOFghcA>? MWPBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU1utUWVNNTJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OTBizszN Mon0NVk4PDR6NUi=
SK-MEL-28 cells MV7GeY5kfGmxbjDhd5NigQ>? MmXBOFghcA>? NGDxeYNCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV2suVUWOLUK4JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUGuPVk2OjZizszN NXHROZhxOTl5NES4OVg>
SK-MEL-5 cells NXSzSIZDTnWwY4Tpc44h[XO|YYm= Ml73OFghcA>? Mm\zRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPLMW1GVC13IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMUm5OVMh|ryP NGG2OYoyQTd2NEi1PC=>
UACC257 cells NH3rWpVHfW6ldHnvckBie3OjeR?= NVLMNnlwPDhiaB?= MY\BcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iVVHDR|I2PyClZXzsd{Bi\nSncjC0PEBpenNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiR1m1NF0{NjF4MkK4JO69VQ>? MlnpNVk4PDR6NUi=
UACC62 cells NWe0O485TnWwY4Tpc44h[XO|YYm= NF32UYU1QCCq NIS5fpRCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gWWFESzZ{IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMEO5PFEh|ryP NGDnTIIyQTd2NEi1PC=>
IGROV1 cells NV32OXpCTnWwY4Tpc44h[XO|YYm= MXO0PEBp NHnRZWdCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTWdTV1ZzIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTJwNUGxPFkh|ryP MlvtNVk4PDR6NUi=
OVCAR-3 cells MmLvSpVv[3Srb36gZZN{[Xl? NUXsfIF4PDhiaB?= NF[0NppCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gU3ZESVJvMzDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1{LkWxNVg6KM7:TR?= NVPSZVhvOTl5NES4OVg>
OVCAR4 cells Ml;FSpVv[3Srb36gZZN{[Xl? NEfke5o1QCCq M{jCOGFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDPWmNCWjRiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OTBizszN MlzNNVk4PDR6NUi=
OVCAR5 cells MUTGeY5kfGmxbjDhd5NigQ>? NX;kU2hOPDhiaB?= NIPze3dCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gU3ZESVJ3IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTZwM{C5OVch|pyv NELrZmwyQTd2NEi1PC=>
OVCAR8 cells NEfiXmJHfW6ldHnvckBie3OjeR?= MWi0PEBp NVHkPGtQSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG9XS0GUODDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1yLkGyOVg6KM7:TR?= NVXSUXJXOTl5NES4OVg>
SKOV3 cells MXfGeY5kfGmxbjDhd5NigQ>? NE\Y[Vg1QCCq NFTQVo5CdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV2tQXjNiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OS57OUWyOkDPxE1? NVfBcVV6OTl5NES4OVg>
786-0 cells Mlf4SpVv[3Srb36gZZN{[Xl? MoTDOFghcA>? NIjH[WVCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gO|g3NTBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5zIN88US=> NF3TfWEyQTd2NEi1PC=>
A498 cells MXnGeY5kfGmxbjDhd5NigQ>? M2LKd|Q5KGh? MXLBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQUS5PEBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2xMlI2QDl|IN88US=> MX[xPVc1PDh3OB?=
ACHN cells NGnQVY1HfW6ldHnvckBie3OjeR?= NEPCWFI1QCCq MUjBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQVPIUkBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2wMlA{OTZ{IN88US=> NHK3b5QyQTd2NEi1PC=>
Caki1 cells NXGwNIE3TnWwY4Tpc44h[XO|YYm= MmLPOFghcA>? MVXBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ3HrbVEh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4xOzF4MjFOwG0> NFf5S2UyQTd2NEi1PC=>
SN12C cells MUDGeY5kfGmxbjDhd5NigQ>? MWS0PEBp NXPZdYxCSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHNPOTKFIHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDHTVUxRTBwMUm5OVMh|ryP MkflNVk4PDR6NUi=
TK10 cells MWHGeY5kfGmxbjDhd5NigQ>? MX[0PEBp NV7rTG9XSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHRMOTBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:PS5yMUG4O{DPxE1? NFLnOXYyQTd2NEi1PC=>
UO31 cells MoDSSpVv[3Srb36gZZN{[Xl? M4j3WFQ5KGh? NWO0T5BoSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHVQOzFiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:OC5zMkW4PUDPxE1? MYGxPVc1PDh3OB?=
PC3 cells NWnq[3hMTnWwY4Tpc44h[XO|YYm= M2\SR|Q5KGh? M2T0OmFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4{OTZ{MzFOwG0> MVSxPVc1PDh3OB?=
DU145 cells M1X1[mZ2dmO2aX;uJIF{e2G7 MVW0PEBp MYrBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iRGWxOFUh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NE4zPTFzOTFOwG0> NXHtfJZuOTl5NES4OVg>
MCF7 cells NUXNR2QxTnWwY4Tpc44h[XO|YYm= MmLoOFghcA>? M4\LS2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVAvODB4M{Gg{txO NGfxPFUyQTd2NEi1PC=>
NCI/ADR-RES cells NGnndm9HfW6ldHnvckBie3OjeR?= MoDkOFghcA>? MXHBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJM2FFWi2URWOgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;MT6yOVg6OyEQvF2= M4npNVE6PzR2OEW4
MDA-MB-231 cells M1u4bmZ2dmO2aX;uJIF{e2G7 Ml3hOFghcA>? Mn3ZRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1OSi1{M{GgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO|YYmsJGdKPTB;Mz65PFExPyEQvF2= MXqxPVc1PDh3OB?=
Hs 578T cells MnvNSpVv[3Srb36gZZN{[Xl? MYC0PEBp Mm\3RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjzJFU4QFRiY3XscJMh[W[2ZYKgOFghcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVA:Oy57OEGwO{DPxE1? NFyzOnAyQTd2NEi1PC=>
MDA-MB-435 cells MUjGeY5kfGmxbjDhd5NigQ>? M1:5d|Q5KGh? M2DyZWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvNEO1JINmdGy|IHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUOuNVYzOjhizszN NFvwSIsyQTd2NEi1PC=>
MDA-N cells NVO2Z2J1TnWwY4Tpc44h[XO|YYm= NWnlWGZNPDhiaB?= MknqRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1PKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVEvOjV6OUOg{txO NUHaTIoyOTl5NES4OVg>
BT549 cells MX3GeY5kfGmxbjDhd5NigQ>? NVrSVndzPDhiaB?= MYXBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQmS1OFkh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUC9NUDPxE1? NHzibpAyQTd2NEi1PC=>
T47D cells M36yNGZ2dmO2aX;uJIF{e2G7 MXe0PEBp MXTBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iVES3SEBk\WyuczDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhT0l3ME2xMlI2QDl|IN88US=> M{f3blE6PzR2OEW4
HepG2 cells MYnDfZRwfG:6aXPpeJkh[XO|YYm= M3L6UVczKGh? NFy1PYlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCHQ{WwQVE5Njh2IN88US=> NWHGZW9HOTl7MUe1Nlg>
A549 cells MoDvR5l1d3SxeHnjbZR6KGG|c3H5 NWrDV4R3PzJiaB?= NIfxenFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEWFNUC9PU44PCEQvF2= NWj6fopzOTl7MUe1Nlg>
LAC cells NUC4d3F3S3m2b4TvfIlkcXS7IHHzd4F6 MmXKO|IhcA>? NGjFenJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBNSUNiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhTUN3ME2zNk4xQSEQvF2= M2LpZlE6QTF5NUK4
HeLa cells NWThTnk1S3m2b4TvfIlkcXS7IHHzd4F6 M{no[VczKGh? NYXLTmx3S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCHQ{WwQVExNjJ4IN88US=> MkLjNVk6OTd3Mki=
MDA-MB-231 cells M4fPUWN6fG:2b4jpZ4l1gSCjc4PhfS=> Mm\XR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDveoVz\XiycnXzd4lv\yC3cn;rbY5ie2VicHzhd41qdm:pZX6gZYN1cX[jdH;yMEBKSzVyPUCuNlEh|ryP NI\KN3IzODN4M{GzNC=>
human ACHN cells NIr6ZW9HfW6ldHnvckBie3OjeR?= MVLBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQVPIUkBk\WyuczDifUBUWkJiYYPzZZktKEeLNUC9Nk4yKM7:TR?= M1HFUlIxPzN{OEGw
PC3 cells NVK2SIZ[TnWwY4Tpc44h[XO|YYm= MkKzRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGDDN{Bk\WyuczDifUBUWkJiYYPzZZktKEeLNUC9OE46PyEQvF2= NVrIfFA1OjB5M{K4NVA>
MDA-MB-231 cells MYXGeY5kfGmxbjDhd5NigQ>? MXzBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVTBMW1DNTJ|MTDj[YxteyCkeTDTVmIh[XO|YYmsJGdKPTB;MD6xOkDPxE1? NIrhO|IzODd|MkixNC=>
FM3A cells NFr1R|RHfW6ldHnvckBie3OjeR?= NUOwO|RPOiCmYYnz NX6zfWt2S3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KG2xdYPlJGZOO0FiY3XscJMh[W[2ZYKgNkBl[Xm|IHL5JINwfWy2ZYKgZ492dnSrbnegZY5idHm|aYOsJGlEPTB;MD6wNFk1KM7:TR?= NWLHSHl3OjF|M{CwNVQ>
HeLa cells NUPiSXBHTnWwY4Tpc44h[XO|YYm= NW[1NpI6S3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMhcW5icILld4Vv[2Vib3[gNlAhfU1idHj5cYllcW6nLDDJR|UxRThwNTFOwG0> MWiyNVM{ODBzNB?=
LLC cells M{\DWWN6fG:2b4jpZ4l1gSCjc4PhfS=> MXiyOEBp MmH5R5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgUGxEKGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDy[ZNignW{aX6gZZN{[XluIFnDOVA:OTRwMjFOwG0> M4fJdVIyPTN4NES4
LLC cells NVmxWlF2S3m2b4TvfIlkcXS7IHHzd4F6 MoKyO|IhcA>? MljiR5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgUGxEKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDy[ZNignW{aX6gZZN{[XluIFnDOVA:OiEQvF2= MV[yNVU{PjR2OB?=
RAW264.7 cells M1zHeWN6fG:2b4jpZ4l1gSCjc4PhfS=> MnfYO|IhcA>? MYTDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W|ZTDSRXczPjRwNzDj[YxteyCjZoTldkA4OiCqcoOgZpkhemW|YYr1dolvKGG|c3H5MEBKSzVyPUOwJO69VQ>? NHvMXXgzOTV|NkS0PC=>
A549 cells M1TJWGN6fG:2b4jpZ4l1gSCjc4PhfS=> NUHvNXhMPzJiaB?= MoDBR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bie3Onc4Pl[EBieyClZXzsJJZq[WKrbHn0fUBi\nSncjC3NkBpenNiYomgW3NVNThiYYPzZZktKEmFNUC9NE4xPDdizszN NIPMN2ozOjJ2OEi1Oi=>
A2780 cells MnTWR5l1d3SxeHnjbZR6KGG|c3H5 M2\mflUh\GG7cx?= M3\5fmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGEzPzhyIHPlcIx{KGGodHXyJFUh\GG7czDifUBOXFRiYYPzZZktKEmFNUC9NE4xOjZizszN M2LHcVIzPzN6NkO2
LMTK cells NWryOohjS3m2b4TvfIlkcXS7IHHzd4F6 NEfqUnc2KGSjeYO= MnrSR5l1d3SxeHnjbZR6KGGpYXnud5QhfGi7bXnkbY5mKGurbnHz[U1l\W[rY3nlcpQhdW:3c3WgUG1VUyClZXzsd{Bi\nSncjC1JIRigXNiYomgUXRVKGG|c3H5MEBKSzVyPUSuOUDPxE1? NHiwbGQzOjd|OE[zOi=>
A549 cells NGn4SG9EgXSxdH;4bYNqfHliYYPzZZk> NV:2fXRXPzJiaB?= NHe5b21EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFczKGi{czDifUBucWO{b4DsZZRmKHKnYXTldkBu\XSqb3SsJGlEPTB;MD6wNVI1KM7:TR?= M1rPeFIzQDR5MEG5
CEM cells MnzuSpVv[3Srb36gZZN{[Xl? NXjlXZNJPzJiaB?= M3z3XGN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDSW0h[2WubIOg[ZhxemW|c3nu[{BpfW2jbjDFUnQyKHS{YX7zdI9zfGW{IHHmeIVzKDd{IHjyd{BjgSClZXzsJINwfW62aX7nJIlvKHC{ZYPlcoNmKG:oIF7CUXBTNCCLQ{WwQVAvQCEQvF2= MVeyNVg6Ojh{OR?=
Hela cells M3i2fWZ2dmO2aX;uJIF{e2G7 M{np[lczKGh? MWXDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDh[pRmeiB5MjDodpMh[nliY3XscEBkd3WwdHnu[{whUUN3ME2wMlA2KM7:TR?= M2TJZVIyQDl{OEK5
CEM/0 cells M1\XXGZ2dmO2aX;uJIF{e2G7 M2P4TVczKGh? NXHwVWw3S3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGNGVS9yIHPlcIx{KGGodHXyJFczKGi{czDifUBk\WyuIHPveY51cW6pLDDJR|UxRTBwMEKyJO69VQ>? MYmyNVg6Ojh{OR?=
L1210/0 cells MUPGeY5kfGmxbjDhd5NigQ>? MnvSOFghcA>? NYfue3BoS3m2b4P0ZZRq[yCjY4Tpeol1gSCjZ3HpcpN1KG2xdYPlJGwyOjFyL{CgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KGOnbHygZ492dnSrbnesJGlEPTB;MD6wNFA6KM7:TR?= Mnj0NlE5QTJ6Mkm=
MCF7 cells M1LGXmN6fG:2b4jpZ4l1gSCjc4PhfS=> MlfBO|IhcA>? MoTqR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC3NkBpenNiYomgV3JDKGG|c3H5MEBKSzVyPUGyMlE6KM7:TR?= NE\PeHIzOzh4N{[wNy=>
HeLa cells MlfJR5l1d3SxeHnjbZR6KGG|c3H5 NEe5[Yc4OiCq MVrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDTVmIh[XO|YYmsJGlEPTB;Nj61JO69VQ>? M17RTlI{QDZ5NkCz
HL60 cells MlGwVJJwdGmoZYLheIlwdiCjc4PhfS=> M1y4elczKGh? MnjtRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKTE[wJINmdGy|IHHzd4V{e2WmIHHzJIdzd3e2aDDpcohq[mm2aX;uJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTB;MD6yOEDPxE1? NWr4U29COjV4NES2O|Q>
SW707 cells MVrQdo9tcW[ncnH0bY9vKGG|c3H5 MWm3NkBp MlTPRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCVV{ewO{Bk\WyuczDhd5Nme3OnZDDhd{Boem:5dHigbY5pcWKrdHnvckBi\nSncjC3NkBpenNiYomgV3JDKG2ndHjv[EwhUUN3ME2yN{45PiEQvF2= MnqyNlU3PDR4N{S=
LoVo cells M{nOdHBzd2yrZnXyZZRqd25iYYPzZZk> MUe3NkBp M3;XWmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTH;Wc{Bk\WyuczDhd5Nme3OnZDDhd{Boem:5dHigbY5pcWKrdHnvckBi\nSncjC3NkBpenNiYomgV3JDKG2ndHjv[EwhUUN3ME2xPU4xPyEQvF2= MnzaNlU3PDR4N{S=
BALB/3T3 cell M{fCXnBzd2yrZnXyZZRqd25iYYPzZZk> Mn7iO|IhcA>? NX3BeHZwSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBud3W|ZTDCRWxDNzOWMzDj[YxteyCjc4Pld5Nm\CCjczDndo94fGhiaX7obYJqfGmxbjDh[pRmeiB5MjDodpMh[nliU2LCJI1mfGixZDygTWM2OD1{Mz65JO69VQ>? NUHxOpByOjV4NES2O|Q>
HFF cells MYjGeY5kfGmxbjDhd5NigQ>? NXfUW|dKPzJiaB?= M1TYO2FvfGmyYYLhd4l1cWNiYXP0bZZqfHliYXfhbY5{fCCWb4jvdIxie22jIHfvcoRqcSCDVFPDJFUxQDN7IHnu[oVkfGWmIHnuJGhHTiClZXzsd{Bi\nSncjC3NkBpenNiYomgZoV1[S2pYXzhZ5Rwe2mmYYPlJJJmeG:{dHXyJIdmdmViYYPzZZktKEWFNUC9NE46OSEQvF2= MX2xO|Y6QDZzOB?=
CCRFCEM cells NYrnSGljTnWwY4Tpc44h[XO|YYm= M1\3XWN6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDR3JHS0WPIHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OD1yLkK5JO69VQ>? MnXKNVc5ODR{M{G=
RXF393 cells M{\yVWZ2dmO2aX;uJIF{e2G7 MmrROFghcA>? MWfBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iUmjGN|k{KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIHHzd4F6NCCJSUWwQVMvQThzMEeg{txO MWKxPVc1PDh3OB?=
HL-60(TB) cells Mn\oSpVv[3Srb36gZZN{[Xl? MVy0PEBp MmrvRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjMMVYxMFSEKTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OD1yLkG5PVU{KM7:TR?= NW\pWVBnOTl5NES4OVg>
L1210 cells MnTuSpVv[3Srb36gZZN{[Xl? NILMPYIyPSCvaX7z MWnJcohq[mm2aX;uJI9nKHSqeX3p[Jlt[XSnIIP5cpRp[XOnIHnuJI1wfXOnIFyxNlExKGOnbHzzJIF{e2W|c3XkJIF{KGmwaHnibZRqd25ib3[geJJqfGm3bTDy[Yxm[XOnIH\yc40hYzVvM1jd[IVwgHm3cnnkbY5mKGGodHXyJJBz\WmwY4XiZZRqd25iZn;yJFE2KG2rboOgZpkhdGmzdXnkJJNkcW62aXzsZZRqd25iY3;1cpRqdmduIFnDOVA:OC5yMEC2JO69VQ>? M2T5e|IyOzNyMEG0
Colo-357 cells MVPGeY5kfGmxbjDhd5NigQ>? NXuzdW0yOTByIN88US=> NXOwbZExOTVibXnudy=> MXXBZ5Rqfmm2eTDheEBOWlB3IHnuJIh2dWGwIFPvcI8uOzV5IHPlcIx{KGG|c3Xzd4VlKGG|IEWtSoRWVVBiYXPjeY12dGG2aX;uJIF1KDFyMDD1UUBi\nSncjCxOUBucW6| M13UO|IxQTNyMUKz
KB cells MmXSR5l1d3SxeHnjbZR6KGG|c3H5 NYjJc2ZpPzJiaB?= NXH4XWpIS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hU0JiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JHNTSiCjc4PhfUwhUUN3ME24MlY6KM7:TR?= M3TNWVI{QDZ5NkCz

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 49 mg/mL (199.03 mM)
Water 49 mg/mL (199.03 mM)
Ethanol 10 mg/mL (40.61 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 246.19
Formula

C9H11FN2O5

CAS No. 50-91-9
Storage powder
Synonyms Deoxyfluorouridine, FDUR, NSC 27640

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02529774 Not yet recruiting Resected Liver Metastases From Colorectal Cancer Ye Xu|Fudan University September 2015 Phase 2|Phase 3
NCT01938729 Active, not recruiting Intrahepatic Cholangiocarcinoma|Peripheral Cholangiocarcinoma|Cholangiolar Carcinoma|Cholangiocellular Carcinoma) (ICC) Memorial Sloan Kettering Cancer Center|Ohio State University|University of Texas Southwestern Medical Center|Washington University School of Medicine September 2013 Phase 1
NCT01862315 Recruiting Intrahepatic Cholangiocarcinoma|Peripheral Cholangiocarcinoma|Cholangiolar Carcinoma|Cholangiocellular Carcinoma Memorial Sloan Kettering Cancer Center|Ohio State University|University of Texas|Washington University School of Medicine May 2013 Phase 2
NCT01749397 Recruiting Stage IV Fallopian Tube Cancer|Stage IV Ovarian Cancer|Stage IV Primary Peritoneal Cancer National Cancer Institute (NCI) December 2012 Phase 1
NCT01692704 Completed Cholangiocellular Carcinoma University of Zurich April 2012 Phase 1|Phase 2
NCT01525069 Recruiting Cholangiocarcinoma|Liver Neoplasms Washington University School of Medicine April 2012 Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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DNA/RNA Synthesis Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID