2,2,2-Tribromoethanol

Synonyms: TBE, Tribromoethanol

2,2,2-Tribromoethanol (TBE, Tribromoethanol) is an organic compound used to anesthetize animals.

2,2,2-Tribromoethanol Chemical Structure

2,2,2-Tribromoethanol Chemical Structure

CAS: 75-80-9

Selleck's 2,2,2-Tribromoethanol has been cited by 1 publication

Purity & Quality Control

Batch: Purity: >97%
97

2,2,2-Tribromoethanol Related Products

Biological Activity

Description 2,2,2-Tribromoethanol (TBE, Tribromoethanol) is an organic compound used to anesthetize animals.
In Vivo
In vivo Tribromoethanol has been proposed as an acceptable anaesthetic in dogs, cats, mice, rats, and gerbils. It possesses a concentration dependent irritant effect. When used at low concentration, it displays good anesthetic effect. A high dose of tribromoethanol is not a suitable anesthetic for major surgery in all mouse strains because of the risk of pathologic changes in the abdominal organs, such as retention of the digestive tract, peritonitis, and fibrinoid adhesion[1][2].
Animal Research Animal Models Male ICR, C57BL/6/Bkl, and BALB/c/Bkl mice
Dosages 200 mg/kg
Administration i.p.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04573205 Not yet recruiting
Tick-borne Encephalitis|Vaccine
Region Örebro County
January 2024 Phase 4
NCT05607394 Recruiting
Tick-borne Encephalitis
University Hospital Strasbourg France
October 24 2022 --
NCT05138055 Recruiting
Tick-Borne Encephalitis European
Sykehuset Telemark|Sykehuset i Vestfold HF|Norwegian Institute of Public Health|Sorlandet Hospital HF|Oslo University Hospital
October 1 2020 --
NCT03932448 Unknown status
Tick-Bite; Fever|Tick Fever|Tick-Borne Diseases|Encephalitis Tick-Borne|Tick Bites
Göteborg University|Sahlgrenska University Hospital Sweden|Vastra Gotaland Region
May 15 2019 --
NCT03971058 Unknown status
Japanese Encephalitis Vaccine
Medical University of Vienna|Valneva Austria GmbH
March 1 2019 Phase 4

Chemical Information & Solubility

Molecular Weight 282.76 Formula

C2H3Br3O

CAS No. 75-80-9 SDF Download 2,2,2-Tribromoethanol SDF
Smiles C(C(Br)(Br)Br)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 57 mg/mL ( (201.58 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 57 mg/mL

Water : 29 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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