HMG-CoA Reductase Inhibitors

Cat.No.	Product Name	Information	Product Citations
S2061	Lovastatin (Mevacor)	Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM, used for lowering cholesterol (hypolipidemic agent).
S2077	Atorvastatin calcium (Lipitor)	Atorvastatin (Lipitor) is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol.	BMC Pharmacol Toxicol, 2013, ahead of print
S1909	Fluvastatin sodium (Lescol)	Fluvastatin sodium inhibits HMG-CoA reductase activity with IC50 of 8 nM.
S3036	Pravastatin sodium	Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.

Cat.No.	Product Name	Solubility (25°C)
Cat.No.	Product Name	Water	DMSO	Ethanol
S2061	Lovastatin (Mevacor)	<1 mg/mL	8 mg/mL	6 mg/mL
S2077	Atorvastatin calcium (Lipitor)	<1 mg/mL	100 mg/mL	<1 mg/mL
S1909	Fluvastatin sodium (Lescol)	1 mg/mL	87 mg/mL	<1 mg/mL
S3036	Pravastatin sodium	89 mg/mL	89 mg/mL	12 mg/mL

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