c-RET Inhibitors

Cat.No.	Product Name	Information	Product Citations
S1107	Danusertib (PHA-739358)	Danusertib (PHA-739358) is an Aurora inhibitor for Aurora A/B/C, Bcr-Abl, c-RET and FGFR with IC50 of 13 nM/79 nM/61 nM, 25 nM, 31 nM and 47 nM, respectively.	Biochem Pharmacol, 2012, 83(4), 452-461 J Pharmacol Exp Ther, 2012, 343(3):617-27
S2692	TG101209	TG101209 is a potent inhibitor of JAK2, Flt3 and RET with IC50 of 6 nM, 25 nM and 17 nM, respectively.
S1244	Amuvatinib (MP-470)	MP-470 (Amuvatinib) is a potent and multi-targeted inhibitor of c-Kit^D816H, PDGFα^V561D and Flt3^D835Y with IC50 of 10 nM, 40 nM and 81 nM, respectively.	Nat Genet, 2012, 44(8):852-60

Product Categories