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Antimetabolites
| Cat.No. | Product Name | Feedback | Added |
|---|---|---|---|
| S1981 | Adenine | Jan 2012 | |
| Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry. | |||
| S1983 | Adenine hydrochloride | Jan 2012 | |
| Adenine hydrochloride is a hydrochloride salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry. | |||
| S1982 | Adenine sulfate | Jan 2012 | |
| Adenine sulfate is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry. | |||
| S1156 | Capecitabine (Xeloda) |  | Feb 2010 |
| Capecitabine (Xeloda) is an orally-administered chemotherapeutic agent (IC50 = 0.7~5 mM) and prodrug of 5-fluorouracil which is a DNA synthesis inhibitor with an IC50 for 5.0 ± 1.8 μM. | |||
| S1199 | Cladribine | May 2010 | |
| Cladribine is an adenosine deaminase inhibitor with an IC50 of about 0.2 μM. | |||
| S1218 | Clofarabine | May 2010 | |
| Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase | |||
| S1200 | Decitabine | May 2010 | |
| Decitabine is an available nucleoside-based DNA methyltransferase (DNMT) inhibitor with IC50 of 490, 400 and 100 nM for A549, LoVo and LoVo-DX cell lines. | |||
| S1299 | Floxuridine (Fludara) | Jun 2010 | |
| Floxuridine (Fludara) is a prodrugs of floxuridine and an oncology agent with an GI50 of 5.1 μM for the inhibition of MDCK/PEPT1. | |||
| S1491 | Fludarabine (Fludara) | Sep 2010 | |
| Fludarabine (Fludara) is a purine analog and a chemotherapy compound with IC50 < 3 μM. | |||
| S1229 | Fludarabine Phosphate(Fludara) | May 2010 | |
| Fludarabine Phosphate (Fludara, 2-F-ara-AMP, FAMP) is a nucleoside analogue and formulated as the monophosphate form of F-ara-AMP(fludarabine, IC50 < 3 μM). | |||
| S1149 | Gemcitabine Hydrochloride | | Feb 2010 |
| Gemcitabine is an antimetabolites inhibiting DNA synthesis(cell IC50 of 0.06 µM). | |||
| S1135 | Pemetrexed (Alimta) | Dec 2009 | |
| Pemetrexed (Alimta) is a thymidylate synthase, DHFR and glycinamide ribonucleotide formyltransferase inhibitor with an IC50 of 25, 34, 220 nM. | |||
| S1192 | Raltitrexed (Tomudex) | Apr 2010 | |
| Raltitrexed (TDX; ZD 1694; Tomudex) is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth. | |||
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Customer's Feedback
| Dongfeng Chen, The Rausing Lab |
| "Your product U0126(Cat.NO S1102) works well in our experiments. I hope I can get more excellent products from your company in future." |
| R.B. Cambridge |
| "I have used the chemical that I bought from you(Selleck,PTC-124) and it worked well.So we will eventually be ordering more." |
| Zhenghe John Wang Assistant Professor, Case Western Reserve University |
| "We have purchased LBH-589, Saha and MS-275 from you and they all worked well." |
| Jenny Sun |
| "We used the LBH-589 in our experiments. The compound is easy to use with excellent reproducibility." |
| Yu Wang, Harvard University |
| "The GDC0449 compound worked very well. The results in my hands are equally good as what's been published. Thanks for this great resource for our research." |
| Dung-Fang Lee |
| "Based on our preliminary data, I found MLN8237 and VX-680 have good effects in inhibiting Aurka-maintaining ESC self-renewal in mouse ES cells." |
Latest Catalog
| May 2010 Selleck Latest Catalog |  |
