New P450 (e.g. CYP17) Inhibitors

Catalog No. Product Name Information
E1650 Opevesostat (ODM208) Opevesostat (ODM208) is the first-in-class, selective, nonsteroidal, oral CYP11A1 inhibitor. ODM208 exhibits a rapid, complete, durable, and reversible inhibition of the steroid hormone biosynthesis in an adrenocortical carcinoma cell model in vitro, in adult noncastrated male mice and dogs, and in patients with CRPC.
E2912 MEHP MEHP (Phthalic acid mono-2-ethylexyl ester) is a competitive inhibitor of CYP2C9 with IC50 of 6.37 μM.
All P450 (e.g. CYP17) Inhibitors