Combinatorial Library/Synthesis for High Throughput Screening

Selleck provides combinatorial libraries and combinatorial synthesis for use in high throughput screening (HTS), target identification/screening in drug discovery, in vitro cell-based high content screening (HCS), cell signaling pathway analysis and other chemical biology applications.

Customize Selleck Chemical Libraries on Demand

All of the synthesized chemical compounds within Selleck’s combinatorial library collections have a purity greater than 98%, and are well characterized with respect to their pharmacologically-activity, biological activity, safety, bioavailability, and additional properties. Many of the small molecule chemicals in our combinatorial libraries have been evaluated in pre-clinical studies or are currently undergoing testing in human clinical trials. As a result, Selleck’s combinatorial libraries offer the greatest potential to screen and identify new drugs.

In addition to the commercial compound library plates, we can partner with you to create a custom compound screening library using Selleck’s combinatorial library collection of over 800 bioactive small molecules tailored to your desired specifications.

You can select compounds, quantities, format (dry/solid or DMSO), plate map and concentration to meet your specific requirement.

Customize your Library

Selleck’s combinatorial libraries are available in two formats for your convenience:
(1) pre-dissolved DMSO solutions   (2) dry solid powder.
In the first format, chemicals are prepared with DMSO solution at a concentration of 10mM in 96-well plates, and can be available in aliquots of 100μL/well or 200μL/well. In the dry solid powder preparation, chemicals are supplied as a dry powder in 96 deep-well plates, with each well containing either 1mg or 2mg of chemicals, depending on your needs

Selleck’s Database Ready for Use

Each kind of small molecule library is supplied with a comprehensive documentation set that contains activity descriptions, plate position maps, physical information, and a structural database file for integration into your compound database.