SUMO

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S8696 2-D08 <1 mg/mL 54 mg/mL <1 mg/mL
Catalog No. Information Product Use Citations Product Validations
S8696New

2-D08

2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation. It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET, KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays.

Tags: SUMO Inhibition | SUMO antibody | SUMO inhibitors | SUMO modulation