CCR

Sigaling Pathway Map

Research Area

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S2003 Maraviroc <1 mg/mL 100 mg/mL 100 mg/mL
S8324 ZK756326 78 mg/mL 39 mg/mL 4 mg/mL
Catalog No. Information Product Use Citations Product Validations
S8324New

ZK756326

ZK756326 is a full agonist of CCR8(Chemokine receptor 8) with an IC50 of 1.8 μM, dose-responsively eliciting an increase in intracellular calcium and cross-desensitizing the response of the receptor to CCL1.

S2003

Maraviroc

Maraviroc is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM in cell-free assays, respectively.

Catalog No. Information Product Use Citations Product Validations
S2003

Maraviroc

Maraviroc is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM in cell-free assays, respectively.

2016, 539(7628):304-308

2014, 74(23):7103-14

2012, 72(15):3839-50

Catalog No. Information Product Use Citations Product Validations
S8324New

ZK756326

ZK756326 is a full agonist of CCR8(Chemokine receptor 8) with an IC50 of 1.8 μM, dose-responsively eliciting an increase in intracellular calcium and cross-desensitizing the response of the receptor to CCL1.